Selected publications

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Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, Aceto N. Neutrophils escort circulating tumour cells to enable cell cycle progression. Nature. Feb 6 2019. PMID: 30728496

Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, & Aceto N. “Circulating tumor cell clustering shapes DNA methylation to enable metastasis seeding”. Cell. (Cover of the journal!). Jan 10 2019. PMID: 30633912

Vetter M, Landin J, Szczerba BM, Castro-Giner F, Gkountela S, Donato C, Krol I, Scherrer R, Balmelli C, Malinovska A, Zippelius A, Kurzeder C, Heinzelmann-Schwarz V, Weber WP, Rochlitz C, & Aceto N. “Denosumab treatment is associated with the absence of circulating tumor cells in breast cancer patients”. Breast Cancer Research. Nov 20 2018. PMID: 30458879

Krol I, Castro-Giner F, Maurer M, Gkountela S, Szczerba BM, Scherrer R, Coleman N, Carreira S, Bachmann F, Anderson S, Engelhardt M, Lane H, Evans TRJ, Plummer R, Kristeleit R, Lopez J, & Aceto N. “Detection of circulating tumor cell clusters in human glioblastoma”. British Journal of Cancer. Aug 1 2018. PMID: 30065256

Aceto N, Toner M, Maheswaran S, Haber DA. “En route to metastasis: circulating tumor cell clusters and epithelial-to-mesenchymal transition”. Trends in Cancer - Cell press (inaugural issue). 2015 Sep 1. PMID: 28741562

Sarioglu FA*, Aceto N*, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan T, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA and Toner M. “A microfluidic device for label-free, physical capture of circulating tumor cell clusters”. *Equal contribution. Nature Methods. 18 May 2015. PMID: 25984697

Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA and Maheswaran S. “Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis”. Cell. 2014 Aug 28. PMID: 25171411

Yu M, Bardia A, Aceto N, Bersani F, Madden MN, Donaldson MC, Desai R, Comaills V, Zheng Z, Brachtel E, Sgroi D, Kupur R, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S and Haber DA. “Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility”. Science. 2014 Jul 11. PMID: 25013076

Aceto N, Sausgruber N, Brinkhaus H, Gaidatzis D, Martiny-Baron G, Mazzarol G, Confalonieri S, Quarto M, Hu G, Balwierz P, Pachkov M, Elledge SJ, van Nimwegen E, Stadler MB, and Bentires-Alj M. “Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop”. Nature Medicine. 2012 Mar 4. PMID: 22388088

Aceto N, Duss S, Macdonald G, Meyer DS, Roloff TC, Hynes NE and Bentires-Alj M. “Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion”. Breast Cancer Research. 2012 Oct 12. PMID: 23062209

Sun T, Aceto N, Meerbrey KL, Kessler JD, Zhou C, Migliaccio I, Nguyen DX, Pavlova NN, Botero M, Huang J, Bernardi RJ, Schmitt E, Hu G, Li MZ, Dephoure N, Gygi SP, Rao M, Creighton CJ, Hilsenbeck SG, Shaw CA, Muzny D, Gibbs RA, Wheeler DA, Osborne CK, Schiff R, Bentires-Alj M, Elledge SJ, Westbrook TF. “Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase”. Cell. IF=33.116. 2011 Mar 4. PMID: 21376233