Selected publications

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Donato C, Kunz L, Castro-Giner F, Paasinen-Sohns A, Strittmatter K, Szczerba BM, Scherrer R, Di Maggio N, Heusermann W, Biehlmaier O, Beisel C, Vetter M, Rochlitz C, Weber WP, Banfi A, Schroeder T, & Aceto N. “Hypoxia triggers the intravasation of clustered circulating tumor cells”.
Cell Rep. Sep 8 2020. PMID: 32905777

Ebright EY, Lee S, Wittner BS, Niederhoffer KL, Nicholson BT, Bardia A, Truesdell S, Wiley DF, Wesley B, Li S, Mai A, Aceto N, Vincent-Jordan N, Szabolcs A, Chirn B, Kreuzer J, Comaills V, Kalinich M, Haas W, Ting DT, Toner M, Vasudevan S, Haber DA, Maheswaran S and Micalizzi DS. “Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis”.
Science. Feb 6 2020. PMID: 32029688

Padmanaban V, Krol I, Suhail Y, Szczerba BM, Aceto N, Bader JS and Ewald AJ. “E-cadherin is required for metastasis in multiple models of breast cancer”.
Nature. Sep 4 2019. PMID: 31485072

Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, & Aceto N. “Neutrophils escort circulating tumor cells to enable cell cycle progression”.
Nature. Feb 6 2019. PMID: 30728496

Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, & Aceto N. “Circulating tumor cell clustering shapes DNA methylation to enable metastasis seeding”.
Cell. (Cover of the journal). Jan 10 2019. PMID: 30633912

Vetter M, Landin J, Szczerba BM, Castro-Giner F, Gkountela S, Donato C, Krol I, Scherrer R, Balmelli C, Malinovska A, Zippelius A, Kurzeder C, Heinzelmann-Schwarz V, Weber WP, Rochlitz C, & Aceto N. “Denosumab treatment is associated with the absence of circulating tumor cells in breast cancer patients”.
Breast Cancer Research. Nov 20 2018. PMID: 30458879

Krol I, Castro-Giner F, Maurer M, Gkountela S, Szczerba BM, Scherrer R, Coleman N, Carreira S, Bachmann F, Anderson S, Engelhardt M, Lane H, Evans TRJ, Plummer R, Kristeleit R, Lopez J, & Aceto N. “Detection of circulating tumor cell clusters in human glioblastoma”.
British Journal of Cancer. Aug 1 2018. PMID: 30065256

Sarioglu FA*, Aceto N*, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan T, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA and Toner M. “A microfluidic device for label-free, physical capture of circulating tumor cell clusters”. *Equal contribution.
Nature Methods. 18 May 2015. PMID: 25984697

Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, & Maheswaran S. “Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis”.
Cell. 2014 Aug 28. PMID: 25171411

Yu M, Bardia A, Aceto N, Bersani F, Madden MN, Donaldson MC, Desai R, Comaills V, Zheng Z, Brachtel E, Sgroi D, Kupur R, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, & Haber DA. “Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility”.
Science. 2014 Jul 11. PMID: 25013076

Aceto N, Sausgruber N, Brinkhaus H, Gaidatzis D, Martiny-Baron G, Mazzarol G, Confalonieri S, Quarto M, Hu G, Balwierz P, Pachkov M, Elledge SJ, van Nimwegen E, Stadler MB, & Bentires-Alj M. “Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop”.
Nature Medicine. 2012 Mar 4. PMID: 22388088

Sun T, Aceto N, Meerbrey KL, Kessler JD, Zhou C, Migliaccio I, Nguyen DX, Pavlova NN, Botero M, Huang J, Bernardi RJ, Schmitt E, Hu G, Li MZ, Dephoure N, Gygi SP, Rao M, Creighton CJ, Hilsenbeck SG, Shaw CA, Muzny D, Gibbs RA, Wheeler DA, Osborne CK, Schiff R, Bentires-Alj M, Elledge SJ, & Westbrook TF. “Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase”.
Cell. 2011 Mar 4. PMID: 21376233